Positive effects on the skin microbiome were associated with reductions in clinical disease activity scores, although the differences compared to vehicle did not reach statistical significance in this relatively small study.
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Effects of a Gel Containing the Defined Microalgae Extract Spiralin® on the Skin Microbiome and Clinical Activity in Atopic Dermatitis: A Double-Blind, Intraindividual Vehicle-Controlled Proof-Of-Concept Study.
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