Reduced Activity of Soluble Fibroblast Activation Protein (sFAP) Represents a Biomarker of Aggressive Disease in Lymphoid Malignancies.

Int J Mol Sci · 2025 · PMC12692083 · PMID 41373408

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0.0670

closest p · 1.3× alpha

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showed a trendp = 0.067so close (0.05 < p ≤ 0.1)

Interestingly, HL showed a similar pattern of activity as these aggressive entities with significantly reduced sFAP activity compared with FL and CLL/SLL ( p = 0.029 and p = 0.024, respectively) and showed a trend toward reduced activity compared with the healthy refence group ( p = 0.067) ( Figure S1B ).

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