Barely Significant
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Clinical Outcomes of Repeated Sodium Polynucleotide Injections in Knee Osteoarthritis: Large-Scale, Retrospective Cohort Study.

J Clin Med · 2025 · PMC12693588 · PMID 41375661

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a significant trendno p-value reported
Although re-administration of PN injections showed a significant trend toward reduced NSAID use for up to six months, this effect was not observed between six and 12 months, and neither single-cycle nor re-administration of PN injections demonstrated favorable outcomes in terms of reducing antidepressant prescriptions.

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