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Correlation of serum uric acid with cancer: a systematic evaluation and dose-response meta-analysis of 43 cohort studies.

Int J Surg · 2025 · PMC12695397 · PMID 40844294

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a negative trendno p-value reported
Subgroup analyses by cancer type revealed that prostate cancer (n≥3) was positively associated with incidence (RR: 1.26; 95% CI: 1.09, 1.46), whereas lung cancer (n≥3) was negatively associated (RR: 0.92; 95% CI: 0.85, 0.99) (Table 3 ). Subgroup analysis by region indicated variability in associations: Japan showed a significant positive association (RR = 1.26; 95% CI: 1.12, 1.42; I 2 = 0%), whereas studies from the UK showed a negative trend (RR = 0.89; 95% CI: 0.78, 1.02; I 2 = 77.8%).

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