Thiorphan reprograms neurons to promote functional recovery after spinal cord injury.

Recipients of thiorphan alone or NPC grafts alone exhibited lesser degrees of forelimb recovery compared with lesioned controls that did not reach statistical significance (Poisson generalized linear model, Wald chi-square = 2.16, P = 0.14 comparing thiorphan with lesion alone, and Wald chi-square = 2.07, P = 0.15 comparing grafts-only with lesion alone; Fig. 2c ).

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