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Loss of Y chromosome in Alzheimer's patients co-occurs with somatic mutations beyond CHIP drivers.

Life Sci Alliance · 2026 · PMC12696397 · PMID 41371958

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Although this difference did not reach statistical significance, most probably due to the small cohort size, it is consistent with other studies, which report that CHIP is associated with reduced risk of AD ( Bouzid et al, 2023 ).

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