Analysis of pathogen spectrum in bronchoalveolar lavage fluid, T lymphocyte depletion, and prognosis in patients with severe pneumonia complicated by ARDS.

Eur J Med Res · 2025 · PMC12696952 · PMID 41318686

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0.0730

closest p · 1.5× alpha

0.0730

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did not reach statistical significanceP = 0.073so close (0.05 < p ≤ 0.1)

All patients received antibiotic treatment, and the rate of initial treatment success in the ARDS group (31.2%) was lower than that in the non-ARDS group (45.0%), but the difference between the two groups did not reach statistical significance (P = 0.073) (Tables 1 and 2 .) As shown in Supplementary Figs. 1–6, laboratory indicators in the ARDS group exhibited significant alterations in inflammatory and immune function markers.

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borderline significanceno p-value reported

Glucocorticoid use (P = 0.067), CD4/CD8 ratio (P = 0.011), and creatinine level (P = 0.066) showed borderline significance.

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