Barely Significant
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Nalmefene enhances the remyelinating ability of nalfurafine when administered therapeutically at very low doses during experimental autoimmune encephalomyelitis.

Clin Transl Immunology · 2025 · PMC12699139 · PMID 41395357

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approached significanceno p-value reported
In contrast, the suboptimal dose NalF and NalM treatments (alone or in combination) did not alter IFN‐γ production significantly although the NalM alone effect approached significance (Figure 6b ).

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