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Does influenza vaccination contribute to the prevention of cardiovascular events? An umbrella review.

Can Commun Dis Rep · 2025 · PMC12699956 · PMID 41393795

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Findings showed a significant reduction in the risk of MI in vaccinated individuals, ranging between 29% (95% CI: 9%–44%) to 34% (95% CI: 7%–54%) with no heterogeneity (I 2 : 0%) ( 24 , 36 ), whereas another SRMA reported a 31% reduction in MI, although it did not reach statistical significance and had substantial heterogeneity (I 2 : 63%) (Figure 3) (( 28 )). • Stroke: Stroke and transient ischemic heart attack (TIA) in influenza vaccinated individuals were evaluated in five (33%) SRMAs.

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