Targeting kinesin family member 20A sensitizes stem-like triple-negative breast cancer cells to standard chemotherapy.

In contrast, canonical Wnt/β-catenin and Hedgehog signaling pathways, both previously implicated in BCSC regulation ( 33 ), did not reach statistical significance in our GSEA for either KIF20A depletion or overexpression, suggesting that KIF20A may regulate BCSCs through Wnt/β-catenin– and Hedgehog-independent signaling in TNBC.

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