Mental health trajectories of adolescents treated with psychotropic medications: insights from the european milestone study.

Mol Psychiatry · 2026 · PMC12700807 · PMID 41107439

Europe PMC DOI

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a clear trendno p-value reported

For the externalising domain based on medication status, the data show a clear trend: patients who had never been medicated displayed the lowest scores, indicating fewer externalising symptoms.

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an increasing trendno p-value reported

However, there was an increasing trend in the association over time, starting at 0.576 at T1 to 0.635 at T4.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.