Differential Causal Effects of Common Analgesics on Breast Cancer Risk and Survival: Evidence from Mendelian Randomization.

Int J Womens Health · 2025 · PMC12701644 · PMID 41395122

Europe PMC DOI

hedged sentence

0.0630

closest p · 1.3× alpha

0.0630

boldest claim

The sentences

did not reach statistical significancep=0.063so close (0.05 < p ≤ 0.1)

For ER- breast cancer, the association with genetically predicted paracetamol use did not reach statistical significance in the IVW analysis (OR=2.75, 95% CI: 0.95–7.97, p=0.063, FDR-adjusted p=0.190) ( Figure 2 and Supplementary Table 1 ).

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