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Clinical Utility of the HELT-E<sub>2</sub>S<sub>2</sub> Score for Risk Stratification in Patients with Acute Decompensated Heart Failure: Insights from the CURE-HF Registry.

Intern Med · 2025 · PMC12702539 · PMID 40335300

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a clear trendno p-value reported
Meanwhile, the JROADHF study (registered in 2013), KCHF study (registered in 2014-2016), and REALITY-AHF study (registered in 2014-2015) reported a mean age of 78 years ( 3 , 17 , 18 ), indicating a clear trend of increasing age among hospitalized patients with ADHF in recent years.

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