LASSO-empowered nomogram integrating nutritional-inflammatory-tumor characteristics predicts immunotherapy outcomes in advanced HCC: Large retrospective cohort.

Front Immunol · 2025 · PMC12702932 · PMID 41403946

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did not reach statistical significanceno p-value reported

Although the prognostic nutritional index (PNI) did not reach statistical significance in multivariate analysis, its inclusion in the model suggests a potential role of nutritional status in modulating immunotherapy response, supporting the hypothesis that nutritional interventions may improve treatment efficacy ( 40 ).

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