Inhibition of immune response reduces pathology in dorsal root ganglia and peripheral nerves in cynomolgus macaques following AAV gene therapy.

Mol Ther Methods Clin Dev · 2025 · PMC12704302 · PMID 41404412

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

For example, we did observe elevations in IL-6 and MCP-1 in the CSF in some subjects compared to their pre-dose values, but these changes did not reach statistical significance, especially when accounting for multiple comparisons.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.