Deciphering precursor cell dynamics in esophageal preneoplasia via genetic barcoding and single-cell transcriptomics.

Proc Natl Acad Sci U S A · 2025 · PMC12704714 · PMID 41337486

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a clear trendno p-value reported

Although the dynamics of pESCCs are not entirely consistent between mouse and human temporal samples, a clear trend emerged: pESCCs are significantly expanded during the early stages of both preneoplasia and neoplasia.

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