Prostaglandin E<sub>2</sub>-EP2/EP4 signaling induces the tumor-infiltrating Treg phenotype for tumor growth.

Proc Natl Acad Sci U S A · 2025 · PMC12704795 · PMID 41343674

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

a negative trendno p-value reported

While GSEA with Pan Cancer TI-Treg signature genes ( 26 ) as a gene set shows a negative trend in the enrichment of gene expression changes in the EP2/EP4 cKO TI-Tregs, the enrichment was not so strong as we expected ( SI Appendix, Fig.

also in 4,201 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Prostaglandin E&lt;sub&gt;2&lt;/sub&gt;-EP2/EP4 signaling induces the tumor-infiltrating Treg phenotype for tumor growth.

The sentences

Prostaglandin E<sub>2</sub>-EP2/EP4 signaling induces the tumor-infiltrating Treg phenotype for tumor growth.