Deficiency of Toll-like receptor 2 is a driver of sex-related compositional and structural rearrangements of membrane lipids.

Although the differences in sialic acid concentration in brain tissue samples between compared groups of experimental animals did not reach statistical significance, the results indicated that a lower amount of gangliosides is sex-related, i.e., a feature of both control and TLR2D female mice when compared with control and TLR2D male mice (Supplementary Fig. 2C).

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