Gut microbiota-driven dysbiosis of the SCFA-immune axis in pediatric allergic rhinitis-constipation comorbidity: mechanisms and synbiotic remodeling.

A reduction of 12.3% was also observed in Escherichia–Shigella , a known pathobiont, though this change did not reach statistical significance. 4.2 Functional reprogramming following synbiotic treatment Functional prediction analysis indicated a metabolic shift from carbohydrate-dominant pathways (e.g., heterolactic fermentation, P = 0.008) toward enhanced lipid and sulfur metabolism after intervention.

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