Glycochenodeoxycholic acid promotes hepatocarcinogenesis by inducing hepatic progenitor cell differentiation into cancer-associated fibroblasts via sphingosine-1-phosphate receptor 2 signalling.

Biomark Res · 2025 · PMC12709717 · PMID 41408647

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In addition, the expression levels of the three marker genes ( FGFBP2 , PDGFRA and RGS5 ) across pseudotime showed a significant trend with the progression of cell differentiation (Supplementary Fig.

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