Cross-frequency coupling patterns during oddball processing in disorders of consciousness: a delta-gamma predominance.

Front Psychol · 2025 · PMC12711717 · PMID 41426413

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hedged sentences

0.3290

closest p · 6.6× alpha

0.3290

boldest claim

The sentences

did not reach statistical significancep = 0.329not close (p > 0.1)

A descriptive trend towards a downshift in the peak coupled amplitude frequency was observed along the consciousness continuum, with median values in the gamma range for HC (39.5 Hz) and MCS patients (35.0 Hz) and in the high-beta range for UWS patients (23.0 Hz), but this trend did not reach statistical significance (Kruskal–Wallis, p = 0.329).

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a possible trendno p-value reported

Although the frequency downshift was not statistically significant ( p = 0.329), the descriptive pattern of a lower peak coupled frequency in UWS compared to HC and MCS suggests a possible trend towards oscillatory slowing along the consciousness continuum.

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