Barely Significant
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Comparative cohort study of pregabalin nortriptyline and pregabalin duloxetine in the management of diabetic peripheral neuropathic pain.

Sci Rep · 2025 · PMC12711948 · PMID 41407775

Europe PMCDOI
2
hedged sentences
0.0010
closest p · 0.0× alpha
0.0010
boldest claim

The sentences

highly significantp < 0.001actually significant
The mean difference was − 2.87 (95% CI: -3.76 to -1.98), also highly significant ( p < 0.001).

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did not reach statistical significanceno p-value reported
In contrast, the PG-NT arm showed a numerically smaller change that did not reach statistical significance, indicating a non-significant trend toward improvement rather than a confirmed antidepressant effect.

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