51 The between-group difference for the change from baseline in trough (4:00 PM) IOP did not reach statistical significance (nominal p =0.080). 51 OSD signs were also reduced during the randomized study, with the least square (LS) mean change from baseline in corneal fluorescein staining (CFS) score being greater with preservative-free latanoprost eye drop emulsion compared with preserved latanoprost ( p <0.001). 51 The
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Fifteen-Month Outcomes of Preservative-Free Latanoprost Cationic Emulsion in Open-Angle Glaucoma and Ocular Hypertension: Phase III Open-Label Extension of a Randomized Trial.
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