According to RT‐qPCR analysis of TAMs, the siMARCO group's mRNA levels of NLRs, including Nlrc5 , Nod1 , Nod2 , Nlrc4 , and Naip2 , showed an increasing trend in comparison to the siNC group (Figure 6D ).
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MARCO+ Tumor-Associated Macrophages Impede CD8+ T Cell Immunity to Facilitate Immunotherapy Resistance in Renal Cell Carcinoma.
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In contrast, the resting CD8+ Trm cells showed a trend toward increased infiltration in the MARCO+ TAM‐high group (Figure 3H,I ).