A risk-stratified model for predicting endometrial atypical hyperplasia and cancer to guide biopsy decisions in asymptomatic postmenopausal women.

Although age at menopause did not reach statistical significance in the multivariable model, we observed a trend toward increased risk with later menopause, which is consistent with the biological hypothesis that prolonged, unopposed estrogen exposure contributes to endometrial carcinogenesis.

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