mRNA vaccines encoding variant forms of Sm-TSP-2 confer protective immunity against Schistosoma mansoni.

NPJ Vaccines · 2025 · PMC12714763 · PMID 41397983

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did not reach statistical significanceno p-value reported

Although IgG titers were elevated in groups immunized with Sm -TSP-2 and Sm- TSP-2-EC2 mRNAs compared to the eGFP mRNA control, the differences did not reach statistical significance, indicating high variability or modest immunogenicity.

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