Toll like receptor agonist effects on human CD8+ T cell activation and expression of T cell checkpoint receptors.

Hum Vaccin Immunother · 2025 · PMC12716034 · PMID 41408773

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showed a trendno p-value reported

Notably, several combinations with TLR8 or TLR9 agonists showed a trend in lowering the expression of CTLA-4 in both CMV- and EBV- specific CD8+ T cells ( Figure 2(C,D) ).

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