IL-21 attenuates liver inflammation by enhancing myeloid-derived suppressor cells immunosuppressive function in chronic HBV infection.

J Transl Med · 2025 · PMC12717690 · PMID 41419948

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0900

boldest claim

The sentences

did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

We also observed a trend toward increased frequency of intrahepatic gMDSCs compared to circulating gMDSCs in both the pBlank and pIL-21 groups, although this trend did not reach statistical significance ( p = 0.06) (Figs. 5 I and 5 J).

also in 111,027 other papers

an increasing trendp = 0.09so close (0.05 < p ≤ 0.1)

Furthermore, we detected significantly higher levels of galectin-9 in circulating MDSCs and an increasing trend ( p = 0.09) in the expression of arginase I in circulating gMDSCs in chronic HBV infected patients than in HC.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.