Barely Significant
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Genome-resolved metagenomics and evolutionary analysis reveal conserved metabolic adaptations in extremophile communities from a copper mining tailing.

Environ Microbiome · 2025 · PMC12717711 · PMID 41419973

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a clear trendno p-value reported
Notably, only a few genes related to the metabolism of sulfur and copper were identified to be under PS ( msrB , cysQ , and csoR genes), indicating a clear trend toward a conservative evolution in the intrinsic mining pathways.

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