Antipsychotic load during olanzapine mono- versus polytherapy and in relation to age.

After 8 weeks, the reduction in the Positive and Negative Syndrome Scale (PANSS) score (primary outcome) was higher in the group combining olanzapine and amisulpride than in the olanzapine plus placebo group, while the difference in PANSS score between the combination group and the amisulpride plus placebo group did not reach statistical significance.

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