In trastuzumab + pertuzumab subgroup, while HER2 IHC 3+ (OR = 8.99), ER+/PR+ (OR = 0.20), and SIRI ≥1.27 (OR = 0.23) were correlated with pCR, cN stage did not reach statistical significance ( p = 0.062).
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Preoperative systemic inflammation response index: Clinicopathologic predictor of pathological complete response in HER2-positive breast cancer patients receiving neoadjuvant systemic therapy.
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0.0620
0.0620