Multi-omics analysis reveals differential benefits of immunotherapy±chemotherapy based on detailed smoking history in advanced non-small cell lung cancer.

J Immunother Cancer · 2025 · PMC12719888 · PMID 41423267

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showed a trendp=0.06so close (0.05 < p ≤ 0.1)

This group also showed a trend toward improved OS in the multivariable analyses (HR=0.80, 95% CI 0.64 to 1.00, p=0.06, figure 3F , online supplemental tables 18 and 21 ).

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