Heart Rate Variability Biofeedback Alleviates Subthreshold Depression by Reconstructing the Brain-Heart Axis via Habenular Network Functional Connectivity Modulation.

CNS Neurosci Ther · 2025 · PMC12720014 · PMID 41424171

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0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

only marginally significantp = 0.059so close (0.05 < p ≤ 0.1)

A similar pattern was observed with PHQ‐9 scores (Figure 4c,g,k,o,s ), although the association with the AMY was only marginally significant ( p = 0.059).

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