Circulating cell free HPVDNA in HPV positive head and neck cancer reveals fast responders and early peakers during treatment.

Sci Rep · 2025 · PMC12722297 · PMID 41419643

Europe PMC DOI

hedged sentences

0.1110

closest p · 2.2× alpha

0.1260

boldest claim

The sentences

failed to reach significancep = 0.111not close (p > 0.1)

There was also a tendency for N0-stage disease to correlate to a lower cfHPV-DNA level (N0: 26.3, N1: 217.8, N2: 253.2, N3: 703.0 median copies/ml, respectively), but this failed to reach significance ( p = 0.111) when comparing N0 to all other N-stages.

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did not reach statistical significancep = 0.126not close (p > 0.1)

However, this difference did not reach statistical significance when comparing T1 with all other T-stages ( p = 0.126, Mann-Whitney U-test).

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