Early genetic evolution of driver mutations in uveal melanoma.

Nat Commun · 2025 · PMC12722419 · PMID 41387680

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hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

near-significantp = 0.06so close (0.05 < p ≤ 0.1)

Conversely, GNA11 mutations were associated with Class 2 tumors ( p = 0.0005), PRAME (+) status ( p = 0.05), increased patient age ( p = 0.002), increased tumor diameter ( p = 0.004) and tumor thickness ( p = 0.002), and they showed a near-significant association with ciliary body involvement ( p = 0.06).

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