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Disrupting cell death: ferroptosis and pyroptosis inhibition in hepatic ischemia-reperfusion injury via modulation of GPX4 and cGAS pathways by deferoxamine and octreotide.

Front Pharmacol · 2025 · PMC12722923 · PMID 41446794

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Although the OCT group displayed a 1.5-fold increase in GPX4 activity, this change did not reach statistical significance when compared to the HIRI group ( Figure 3C ).

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