After simultaneous adjustment in multivariate Cox model, age (HR = 1.05, 95% CI 1.02–1.08, P = 0.002) and low WBC (HR = 0.38, 95% CI 0.17–0.82, P = 0.014) were still independently associated with HCC occurrence, whereas C4 and CIV did not reach statistical significance (C4: HR = 1.09, 95% CI 0.52–2.31, P = 0.82; CIV: HR = 0.52, 95% CI 0.16–1.73, P = 0.29; Table 5 ).
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The association between intrahepatic malignant tumors and hepatitis B-related pathological cirrhosis: a retrospective cohort study.
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In contrast, C4 (HR = 1.090, 95% CI 0.517–2.310, P = 0.817), and CIV (HR = 0.523, 95% CI 0.158–1.730, P = 0.287) failed to achieve significance in the Cox model.