Barely Significant
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Prenatal Exposure to PM<sub>2.5</sub> Increased Vulnerability to a Second Hit of a High-Fat Diet in Mouse Offspring.

Environ Health (Wash) · 2025 · PMC12723540 · PMID 41446774

Europe PMCDOI
2
hedged sentences
0.0763
closest p · 1.5× alpha
0.0951
boldest claim

The sentences

did not reach statistical significanceP = 0.0763so close (0.05 < p ≤ 0.1)
Despite a slight decrease in body weight gain observed following 18-day exposure to PM 2.5 , this change did not reach statistical significance ( P = 0.0763) ( Figure S1B ).

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an increasing trendP = 0.0951so close (0.05 < p ≤ 0.1)
The offspring on an HFD displayed a time-dependent rise in body weight, and the prenatal PM 2.5 exposed offspring showed an even more significant increase in body weight ( Figure A). Moreover, the PM-HFD offspring exhibited an increasing trend in body weight gain compared to FA-HFD offspring after 13 weeks of HFD feeding ( P = 0.0951) ( Figure C).

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