The difference in survival did not reach statistical significance as assessed by both the Mantel-Cox ( P = 0.054) and Gehan-Breslow-Wilcoxon test ( P = 0.051), though both tests trend towards improved survival with the 1871 IgG1 ( Fig. 5D ; Fig.
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Human antibody targeting of coronavirus spike S2 subunit is associated with protection mediated by Fc effector functions.
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