Utility of blood DNA methylation and immune cell-type estimates to identify clinically relevant links between immunity and health conditions in a large cohort.

Front Immunol · 2025 · PMC12727583 · PMID 41451225

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hedged sentence

0.0018

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0.0018

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nominally significantp=0.00175actually significant

In addition, because CD4T and CD8T showed nominally significant associations with hsCRP, we also tested these interactions in chronic pain and found that CD4T, but not CD8T, positively interacted with hsCRP (beta=2.5, p=0.00175; n=820; Figure 1E ) in chronic pain.

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