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Editorial: The impact of lipid metabolism on cancer progression and metastasis.

Front Med (Lausanne) · 2025 · PMC12727928 · PMID 41451093

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The meta-analytic findings indicate that lower HDL-C levels show a consistent trend toward poorer disease-free survival (DFS) and overall survival (OS), but pooled hazard ratios did not reach statistical significance (DFS: HR = 1.05, 95% CI 0.87–1.28; OS: HR = 1.10, 95% CI 0.83–1.47).

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