However, for PM 2.5 , eight studies were implemented under the random-effects model, the pooled effect estimate was substantially attenuated from a borderline significant to non-significant (OR = 0.89, 95% CI: 0.70–1.12; original OR = 1.23, 95% CI: 1.00–1.51), this indicates that, after accounting for publication bias, the initial positive association was no longer significant, and the results support no significant association between PM 2.5 and adolescent asthma. 4.
← all excerpts
Outdoor air pollutants and asthma risk in adolescents: evidence from a systematic review and meta-analysis.
4
—
—
The sentences
In contrast, the pooled estimate for particulate matter with diameter ≤ 2.5 micrometers (PM 2.5 ), particulate matter with diameter ≤ 10 micrometers (PM10), and sulfur dioxide (SO 2 ) did not reach statistical significance, These non-significant results, however, were accompanied by considerable between-study heterogeneity ( I 2 = 32.3% for PM2.5, 76.5% for PM10, and 53.6% for SO2), reflecting substantial inconsistency across the included studies and precluding a definitive conclusion regarding the absence of an association.
Long-term exposure ( n = 7) showed borderline significance (random effects: aOR = 1.12), whereas the single short-term exposure study reported aOR = 1.03. 3.5.3.
PM10 (8 studies) The fixed-effects model indicated a marginally significant association (aOR = 1.04, 95% CI: 1.01–1.07), but heterogeneity was high ( I 2 = 76.5%).