Impact of comorbidities on treatment management and prognosis in patients with anaplastic thyroid cancer (ATC).

J Cancer Res Clin Oncol · 2025 · PMC12728151 · PMID 41436662

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did not achieve significanceno p-value reported

All factors included in the multivariate analysis did not achieve significance (see Table 2 ).

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showed a trendno p-value reported

KPS (> 70%, p = 0.06) and type of therapy ( p = 0.087) showed a trend in multivariate analysis.

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highly significantno p-value reported

Since age and occurrence of comorbidities are closely related, a combination of both covariates within the age-adapted Charlson Comorbidity Index (aaCCI) has shown to be a highly significant predictor of prognosis (Charlson et al. 1994 ).

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