From trigeminal ganglion to cortex: ATG7 emerges as a key integrator of migraine pathways via multi-omics profiling.

In the S1HL brain tissue, WB results showed that compared with the control group, the protein level of LC3-II in the model group exhibited an increased trend, while the expression of both LC3-I and p62 showed a decreased trend, although these changes did not reach statistical significance ( P > 0.05) (Fig. 9 b-d).

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Western blot analysis revealed that in the S1HL brain region of migraine model mice, the protein level of LC3-II showed an increasing trend, while the expressions of both LC3-I and p62 exhibited decreasing trends compared to the control group.

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