The Protective Effect of Zinc Supplementation Against Oxidative Stress and Oxidative Modifications of Cellular Macromolecules in the Mandibular Bone of Rats Exposed to Cadmium.

Although the median values for specific parameters (CAT, GPx, and H 2 O 2 ) in the Cd5 and Cd50 groups clearly differed, the difference did not reach statistical significance.

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The demonstration, within an experimental model of moderate and relatively high human exposure to Cd, that Zn supplementation exerts a protective effect on mandibular bone disorders caused by this toxic metal, attributable to its capacity to prevent oxidative stress and its sequelae, constitutes the most important and practically significant conclusion of this study.

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