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Drug-Induced Partial Immunosuppression for Preclinical Human Tumor Xenograft Models.

Cancers (Basel) · 2025 · PMC12730912 · PMID 41463273

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a positive trendno p-value reported
Similar dynamics were observed for body weight: a loss was recorded by day 5, followed by a positive trend of weight gain, indicating the onset of recovery and systemic compensation.

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The dynamics of the relative counts of both T-helper (CD3 + CD4 + ) and T-cytotoxic (CD3 + CD8 + ) cells generally mirrored the changes in the total T-lymphocyte (CD3 + ) population; however, the differences did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.