Clinical Symptom Resolution Following PCR-Guided vs. Culture and Susceptibility-Guided Management of Complicated UTI: How Time-To-Antibiotic Start and Antibiotic Appropriateness Mediate the Benefit of Multiplex PCR-An Ad Hoc Analysis of NCT06996301.

Other symptom categories (fever, suprapubic/pelvic pain, CVA tenderness, nausea/vomiting) showed numerically larger reductions in the PCR arm (ranging from ~88–95% reductions) but did not reach statistical significance after accounting for small absolute counts for some symptoms (e.g., fever, nausea).

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