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Preclinical Evaluation of the Assembly Modulator PAV-615 in a Mouse Model of <i>C9orf72</i>-Associated ALS/FTD.

Cells · 2025 · PMC12732003 · PMID 41440030

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PAV-615 treatment also led to a decrease in poly(GA) levels in 149R mice, although this reduction did not reach statistical significance ( Figure 3 D,G).

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