In addition, although some pooled estimates reached statistical significance, TSA consistently demonstrated that the pooled estimate did not reach statistical significance when considering inflation of type 1 error, and the accrued information size was far below required thresholds, indicating that the available evidence is insufficient to support confirmatory conclusions.
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Effect of Local Anesthetics on Experimental Postoperative Adhesion: A Systematic Review and Meta-Analysis with Trial Sequential Analysis.
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