Baihe Dihuang Tang Exerts Antidepressant Effects via Modulation of MAOA-Mediated Serotonin Metabolism and Synaptic Plasticity.

Pharmaceuticals (Basel) · 2025 · PMC12736097 · PMID 41471275

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did not reach statistical significancep < 0.05actually significant

At the protein level, BDNF exhibited a trend of upregulation consistent with mRNA changes but did not reach statistical significance. p-TrkB protein levels were reduced in CRS mice ( p < 0.05 vs. control), and BDT treatment significantly reversed this decrease ( p < 0.01 vs.

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